CD46 anticorps (APC)

N° du produit ABIN7566533

L’anticorps Souris Monoclonal anti-CD46 a été validé pour FACS. Il convient pour détecter CD46 dans des échantillons de Humain.

Aperçu rapide pour CD46 anticorps (APC) (ABIN7566533)

Antigène: CD46

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD46 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Clone: TRA-2-10

Détail du produit anti-CD46 anticorps (APC)

Fonction: APC Anti-Human CD46 Antibody[TRA-2-10]

Isotype: IgG1, kappa

Information d'application

Indications d'application: Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.
FCM: 5 µL/test

Commentaires:

Matching Isotype Control: (ABIN7469762)

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Stock: 4 °C

Stockage commentaire: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Date de péremption: 12 months

Détails sur CD46

Antigène: CD46

Autre désignation: CD46

Sujet: Complementmembranecofactorprotein,measlesvirusreceptor,MCP,CD46 is a transmembrane protein that is known as a complement membrane cofactor protein, MCP, and measles virus receptor. It is widely expressed on leukocytes, platelets, epithelial cells, and fibroblasts. Multiple isoforms of CD46 have been reported with molecular weights ranging from 45-75 kD. CD46 binds complement components C3b and C4b and has been reported to play a role in T cell regulation. In addition to the complement components, CD46 has been shown to interact with moesin, c-Src, tetraspanin 4, c-Yes, and integrin β1. CD46 is also known to be a cellular receptor for human measles virus and human herpes virus-6 as well as other human pathogens, such as Streptococcus pyogenes. Defects in CD46 have been associated with hemolytic-uremic syndrome.

ID gène: 4179

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization